OnlineMedReviews

Best NAD+ Therapy Of 2026

We compared the leading telehealth NAD+ providers on real all-in cost, physician oversight and delivery — review our ranked picks below.

Updated August 29, 2026

We earn a commission from the offers on this page, which may impact how and where they appear.Advertiser Disclosure

We may earn a commission from partner links on this site, and some listed products are offered by companies affiliated with our publisher. This does not affect our editorial scoring methodology.Rankings reflect our published scoring methodology. See our full advertising disclosure.

By OMR Editorial Team · Health & Telehealth Research

These statements have not been evaluated by the Food and Drug Administration. NAD+ therapy products listed on this page are compounded medications, which are not approved or evaluated for safety, effectiveness or quality by the FDA. Treatment requires a virtual consultation with a licensed telehealth provider, who will determine whether a prescription is appropriate. Individual results may vary.

  1. Best Overall
    1
    RenuviaRX

    RenuviaRX NAD+

    Physician-supervised NAD+ injections without a membership fee

    • Lowest first-month price we verified ($49)
    • No membership fee on top of medication
    • Physician approval typically within hours, not days
    9.8
    Outstanding
    $49/first month
    Check Availability
    Limited Time Offer: First Month Just $49
    On RenuviaRX's website
    Show details, pros & cons ▾

    Pros

    • Lowest first-month price we verified ($49)
    • No membership fee on top of medication
    • Physician approval typically within hours, not days
    • Unlimited provider messaging and all supplies included
    • Free cold-chain priority shipping; pause or cancel anytime

    Cons

    • Injection only — no nasal spray or oral option
    • Not available in Alaska, Mississippi or New Jersey

    Key facts

    Consult:
    Free physician review, approval in ~2–4 hrs
    Membership fee:
    None
    Shipping:
    Free cold-chain overnight, arrives ~2 days
    Availability:
    47 states (not AK, MS, NJ)

    $49 first month on a 3-month plan, then $199/mo. No membership fee.

    Pricing transparency9.8
    Provider access9.9
    Speed & shipping9.6
    Product quality9.8
    Why we picked it: RenuviaRX pairs the lowest verified entry price of any injection-first NAD+ provider with genuinely fast physician review and no recurring membership fee — the line item that quietly inflates most competitors' real monthly cost. Pharmaceutical-grade NAD+ is compounded in US pharmacies and third-party lab verified, and unlimited provider messaging is included.
  2. Most Delivery Options
    2
    AgelessRx

    AgelessRx NAD+

    The longevity pioneer with injections, nasal spray and patches

    • Widest range of forms — injection, nasal spray, weekly patch
    • Longevity-specialist platform with strong review volume
    • No membership fee
    9.0
    Very good
    $125/month
    View Options
    On AgelessRx's website
    Show details, pros & cons ▾

    Pros

    • Widest range of forms — injection, nasal spray, weekly patch
    • Longevity-specialist platform with strong review volume
    • No membership fee

    Cons

    • Injections cost notably more than newer entrants
    • Recurring complaints about shipping delays and support responsiveness

    Key facts

    Consult:
    Included, async provider review
    Membership fee:
    None
    Shipping:
    Cold-packed, ~2 business days
    Standout:
    Only provider with iontophoresis patches

    Nasal spray from $125/mo; injections from $235/mo; patches from $160/mo.

    Pricing transparency8.4
    Provider access9.0
    Speed & shipping8.2
    Product quality9.4
    Why we picked it: AgelessRx effectively created the DTC NAD+ category and still offers the widest choice of delivery forms — the pick if you want NAD+ without needles. Its longevity-clinic DNA (rapamycin, biological-age testing) gives it more scientific depth than most.
  3. 3
    EdenBest Form Flexibility

    Eden NAD+

    Injections, spray and patches — but budget for the membership

    • Injection, nasal spray and transdermal patch options
    • Slick app-based experience; easy bundling with other programs
    8.4
    Good
    $119/month
    Learn More
    On Eden's website
    Show details, pros & cons ▾

    Pros

    • Injection, nasal spray and transdermal patch options
    • Slick app-based experience; easy bundling with other programs

    Cons

    • Required membership adds $99/mo to the real price
    • Advertised prices can feel misleading until checkout

    Key facts

    Consult:
    Included with membership
    Membership fee:
    $99/mo after first month
    Pharmacies:
    503A/503B US partners
    Standout:
    Bundles with metabolic programs

    Plans from $119/mo + required membership ($39 first month, then $99/mo).

    Pricing transparency7.6
    Provider access8.8
    Speed & shipping8.6
    Product quality8.8
    Why we picked it: Eden matches AgelessRx on delivery-form choice and runs a polished, modern care experience. The catch is the required membership — add $99/mo to any advertised price to get your true cost.
  4. 4
    Joi + BlokesBest With Lab Work

    Joi + Blokes NAD+

    NAD+ with optional deep lab testing and health coaching

    • Cheapest long-term injection pricing on 12-month plans
    • HSA/FSA eligible; refund if not approved
    • Optional labs add real clinical guidance
    8.2
    Good
    $89/month
    Learn More
    On Joi + Blokes's website
    Show details, pros & cons ▾

    Pros

    • Cheapest long-term injection pricing on 12-month plans
    • HSA/FSA eligible; refund if not approved
    • Optional labs add real clinical guidance

    Cons

    • Lab push adds cost and friction to onboarding
    • Smaller brand with less review history

    Key facts

    Consult:
    Licensed-provider assessment, sync or async
    Membership fee:
    None (labs optional)
    HSA/FSA:
    Eligible
    Guarantee:
    Full refund if provider declines

    Injections $172/mo (as low as $89/mo on 12-month plans); nasal spray $150/mo.

    Pricing transparency8.0
    Provider access8.6
    Speed & shipping8.0
    Product quality8.6
    Why we picked it: Joi + Blokes wraps NAD+ in a broader optimization program — optional blood panels unlock a health coach and clinician guidance, and long-term plans get genuinely cheap. Good fit if you want data with your protocol.
  5. 5
    Ivím Health

    Ivím Health NAD+

    App-based NAD+ care — strong experience, membership-heavy pricing

    • Polished app with responsive care team
    • Easy add-on for existing Ivím weight-loss patients
    7.8
    Fair
    $249/month
    Learn More
    On Ivím Health's website
    Show details, pros & cons ▾

    Pros

    • Polished app with responsive care team
    • Easy add-on for existing Ivím weight-loss patients

    Cons

    • Most expensive all-in monthly cost here
    • Billing and cancellation complaints on consumer boards

    Key facts

    Consult:
    Provider consult via membership
    Membership fee:
    $74.99/mo, required
    Protocol:
    Once-weekly subQ injection
    Standout:
    Full-featured mobile app

    $249/1-month program + required $74.99/mo membership.

    Pricing transparency7.0
    Provider access8.4
    Speed & shipping8.0
    Product quality8.4
    Why we picked it: Ivím delivers a genuinely polished app-based care experience, but the required membership makes it the most expensive way to get NAD+ on this list. Worth it mainly if you're already an Ivím patient.

These statements have not been evaluated by the Food and Drug Administration. NAD+ therapy products listed on this page are compounded medications, which are not approved or evaluated for safety, effectiveness or quality by the FDA. Treatment requires a virtual consultation with a licensed telehealth provider, who will determine whether a prescription is appropriate. Individual results may vary.

Compare all 5 providers

#ProviderScoreFromFormsBest for
1RenuviaRX9.8$49/first monthInjectionBest OverallVisit
2AgelessRx9.0$125/monthInjection, Nasal spray, PatchMost Delivery OptionsVisit
3Eden8.4$119/monthInjection, Nasal spray, PatchBest Form FlexibilityVisit
4Joi + Blokes8.2$89/monthInjection, Nasal sprayBest With Lab WorkVisit
5Ivím Health7.8$249/monthInjection—Visit

Why NAD+ is having a moment

NAD+ sits at the center of how your cells make energy — and your natural supply declines steadily with age, with research linking lower NAD+ levels to fatigue, slower recovery and brain fog. That’s why NAD+ restoration has moved from longevity-clinic IV lounges to mainstream telehealth: what once required a $500+ infusion appointment can now be a physician-prescribed home protocol costing a fraction of that.

What actually separates providers

After comparing pricing, intake flows and care models across the market, three things separate the best NAD+ programs from the rest:

The real monthly price. Advertised prices are rarely what you pay. Several major providers require a membership on top of the medication — $99/mo at Eden, $74.99/mo at Ivím — which can nearly double the true cost. Our rankings score the all-in number, not the headline.

Physician access. The best programs include the provider consultation, respond in hours rather than days, and let you message a clinician whenever you need a protocol adjustment — without per-visit fees.

Cold-chain shipping. NAD+ is temperature-sensitive. Providers that ship cold-packed overnight with supplies included remove the most common failure point in home protocols.

What you should expect to pay

Entry pricing across reputable providers runs from roughly $105 to $350 per month depending on the form and dose. First-month promotions are common — RenuviaRX’s $49 first month is the most aggressive we verified — and long-commitment plans (like 12-month terms at Joi + Blokes) can bring injections under $90/mo if you’re certain you’ll stick with the protocol.

Why start now rather than later

NAD+ decline is gradual, which is exactly why people ignore it — the difference between 35 and 45 sneaks up. The case for starting a supervised protocol earlier is that you establish a baseline with a physician, learn how your body responds while the stakes are low, and adjust from there. The case for waiting: the human evidence base is still maturing. A licensed provider consultation — included free with most programs on this page — is the right place to weigh both.

Featured Partner Offer
NAD+ Starting at $49 First Month

Physician-supervised NAD+ injections without a membership fee — see if you qualify in minutes.

Get Started
On RenuviaRX's website

Frequently asked questions

What is NAD+ therapy?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell that plays a central role in energy metabolism and cellular repair. NAD+ levels decline with age, and NAD+ therapy aims to restore them through injections, nasal sprays, patches or oral precursors. Telehealth NAD+ programs pair the medication with a licensed provider consultation.

Is NAD+ therapy FDA-approved?

No. NAD+ therapy products sold through telehealth providers are compounded medications prepared by licensed US pharmacies. Compounded medications are not approved or evaluated for safety, effectiveness or quality by the FDA. A licensed provider determines whether a prescription is appropriate for you.

How much does NAD+ therapy cost per month?

Across the providers we compared, real all-in pricing runs from about $105 to over $320 per month. Watch for membership fees — several providers add $75–$99 per month on top of the advertised medication price. RenuviaRX had the lowest verified entry price at $49 for the first month with no membership fee.

Injections, nasal spray or patches — which form is best?

Subcutaneous injection is the most common form and delivers the most consistent dosing. Nasal sprays and patches (offered by AgelessRx and Eden) avoid needles but typically deliver smaller amounts. If needles are a dealbreaker, choose a provider with alternative forms; otherwise most protocols center on 2–3 small subQ injections per week.

How fast will I feel results?

Providers commonly report that patients notice energy changes within one to two weeks and mental-clarity effects by week three, but individual results vary significantly and robust clinical evidence in humans is still developing. No outcome is guaranteed.

Sources

  1. RenuviaRX — NAD+ Therapy
  2. AgelessRx — NAD+ products
  3. Eden — NAD+ treatment
  4. Joi + Blokes — NAD+
  5. Ivím Health — NAD+

Providers are scored on pricing transparency, provider access, speed & shipping, and product quality. Pricing verified August 2026. Read our full scoring methodology.