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Best NAD+ Therapy Of 2026

We compared the leading telehealth NAD+ providers on real all-in cost, physician oversight and delivery - review our ranked picks below.

Updated August 29, 2026

By Claire Bennett · Health & Longevity Writer

The advertised price of NAD+ therapy is a trap: membership fees and add-ons can nearly double what you actually pay each month. So we went through every intake flow ourselves, verified the real all-in numbers on each provider's own website, and ranked the five injection programs that deliver. Our top pick starts at $49 for your first month - with nothing stacked on top.

What we checked:True all-in pricing & plan termsProvider access & review speedShipping speed & discretionProduct quality & sourcingOur methodology

These statements have not been evaluated by the Food and Drug Administration. NAD+ therapy products listed on this page are compounded medications, which are not approved or evaluated for safety, effectiveness or quality by the FDA. Treatment requires a virtual consultation with a licensed telehealth provider, who will determine whether a prescription is appropriate. Individual results may vary. We may earn a commission from partner links on this page. Advertiser Disclosure

  1. Best Overall
    1
    RenuviaRX logo

    RenuviaRX NAD+

    Physician-supervised NAD+ injections without a membership fee

    • Lowest first-month price we verified ($49)
    • No membership fee on top of medication
    • Injection-only lineup - the one form that delivers a full, measurable dose
    9.8
    Outstanding
    $49/first month
    Check Availability
    Limited Time Offer: First Month Just $49
    On RenuviaRX's website
    Show details, pros & cons ▾

    Pros

    • Lowest first-month price we verified ($49)
    • No membership fee on top of medication
    • Injection-only lineup - the one form that delivers a full, measurable dose
    • Physician approval typically within hours, not days
    • Unlimited provider messaging and all supplies included
    • Free cold-chain priority shipping; pause or cancel anytime

    Cons

    • The $49 intro price requires a 3-month plan
    • Not available in Alaska, Mississippi or New Jersey

    Key facts

    Consult:
    Free physician review, approval in ~2-4 hrs
    Membership fee:
    None
    Shipping:
    Free cold-chain overnight, arrives ~2 days
    Availability:
    47 states (not AK, MS, NJ)

    $49 first month on a 3-month plan, then $199/mo. No membership fee.

    Pricing transparency9.8
    Provider access9.9
    Speed & shipping9.6
    Product quality9.8
    Why we picked it: RenuviaRX has the lowest verified entry price of any injection-first NAD+ provider, physician review in hours, and no membership fee - the line item that doubles the real monthly cost at several competitors. Pharmaceutical-grade NAD+ is compounded in US pharmacies and third-party lab verified, and unlimited provider messaging is included.
  2. Longevity Specialist
    2
    AgelessRx logo

    AgelessRx NAD+

    The longevity clinic that pioneered DTC NAD+ injections

    • Category pioneer with the largest review volume in NAD+
    • Longevity-specialist platform (rapamycin, biological-age testing)
    • No membership fee
    9.0
    Very good
    $235/month
    View Options
    On AgelessRx's website
    Show details, pros & cons ▾

    Pros

    • Category pioneer with the largest review volume in NAD+
    • Longevity-specialist platform (rapamycin, biological-age testing)
    • No membership fee

    Cons

    • Injections cost notably more than newer entrants
    • Recurring complaints about shipping delays and support responsiveness

    Key facts

    Consult:
    Included, async provider review
    Membership fee:
    None
    Shipping:
    Cold-packed, ~2 business days
    Standout:
    Longevity platform - rapamycin, biological-age testing

    NAD+ injections from $235/mo; intro promos drop the first month as low as $79.

    Pricing transparency8.4
    Provider access9.0
    Speed & shipping8.2
    Product quality9.4
    Why we picked it: AgelessRx created the DTC NAD+ injection category and pairs it with the deepest longevity toolkit on this list - rapamycin protocols and biological-age testing under the same roof. You pay a premium over newer entrants for that pedigree.
  3. 3
    Eden logoBest Program Bundles

    Eden NAD+

    Polished app-based care - but budget for the membership

    • Slick app-based experience; easy bundling with other programs
    • 503A/503B US partner pharmacies
    8.4
    Good
    $186/month
    Learn More
    On Eden's website
    Show details, pros & cons ▾

    Pros

    • Slick app-based experience; easy bundling with other programs
    • 503A/503B US partner pharmacies

    Cons

    • Required membership adds $99/mo to the real price
    • Advertised prices can feel misleading until checkout

    Key facts

    Consult:
    Included with membership
    Membership fee:
    $99/mo after first month
    Pharmacies:
    503A/503B US partners
    Standout:
    Bundles with metabolic programs

    Injections from ~$186/mo on a 3-month plan + required membership ($39 first month, then $99/mo).

    Pricing transparency7.6
    Provider access8.8
    Speed & shipping8.6
    Product quality8.8
    Why we picked it: Eden runs a polished, modern care experience and makes it easy to bundle NAD+ injections with its metabolic programs. The catch is the required membership - add $99/mo to any advertised price to get your true cost.
  4. 4
    Joi + Blokes logoBest With Lab Work

    Joi + Blokes NAD+

    NAD+ with optional deep lab testing and health coaching

    • Cheapest long-term injection pricing on 12-month plans
    • HSA/FSA eligible; refund if not approved
    • Optional labs add real clinical guidance
    8.2
    Good
    $89/month
    Learn More
    On Joi + Blokes's website
    Show details, pros & cons ▾

    Pros

    • Cheapest long-term injection pricing on 12-month plans
    • HSA/FSA eligible; refund if not approved
    • Optional labs add real clinical guidance

    Cons

    • Lab push adds cost and friction to onboarding
    • Smaller brand with less review history

    Key facts

    Consult:
    Licensed-provider assessment, sync or async
    Membership fee:
    None (labs optional)
    HSA/FSA:
    Eligible
    Guarantee:
    Full refund if provider declines

    Injections $172/mo, as low as $89/mo on 12-month plans.

    Pricing transparency8.0
    Provider access8.6
    Speed & shipping8.0
    Product quality8.6
    Why we picked it: Joi + Blokes wraps NAD+ in a broader optimization program - optional blood panels unlock a health coach and clinician guidance, and 12-month plans drop injections to $89/mo. Built for men who want data with their protocol.
  5. 5
    Ivím Health logo

    Ivím Health NAD+

    App-based NAD+ care - strong experience, membership-heavy pricing

    • Polished app with responsive care team
    • Easy add-on for existing Ivím weight-loss patients
    7.8
    Fair
    $249/month
    Learn More
    On Ivím Health's website
    Show details, pros & cons ▾

    Pros

    • Polished app with responsive care team
    • Easy add-on for existing Ivím weight-loss patients

    Cons

    • Most expensive all-in monthly cost here
    • Billing and cancellation complaints on consumer boards

    Key facts

    Consult:
    Provider consult via membership
    Membership fee:
    $74.99/mo, required
    Protocol:
    Once-weekly subQ injection
    Standout:
    Full-featured mobile app

    $249/1-month program + required $74.99/mo membership.

    Pricing transparency7.0
    Provider access8.4
    Speed & shipping8.0
    Product quality8.4
    Why we picked it: Ivím's app-based care experience is polished, but the required membership makes it the most expensive way to get NAD+ on this list. Worth it mainly if you're already an Ivím patient.

These statements have not been evaluated by the Food and Drug Administration. NAD+ therapy products listed on this page are compounded medications, which are not approved or evaluated for safety, effectiveness or quality by the FDA. Treatment requires a virtual consultation with a licensed telehealth provider, who will determine whether a prescription is appropriate. Individual results may vary.

Compare all 5 providers

#ProviderScoreFromFormsBest for
1RenuviaRX9.8$49/first monthInjectionBest OverallVisit
2AgelessRx9.0$235/monthInjectionLongevity SpecialistVisit
3Eden8.4$186/monthInjectionBest Program BundlesVisit
4Joi + Blokes8.2$89/monthInjectionBest With Lab WorkVisit
5Ivím Health7.8$249/monthInjection-Visit

Why NAD+ therapy is booming

NAD+ sits at the center of how your cells make energy - and your natural supply declines steadily with age, with research linking lower NAD+ levels to fatigue, slower recovery and brain fog. That’s why NAD+ restoration has moved from longevity-clinic IV lounges to mainstream telehealth: what once required a $500+ infusion appointment can now be a physician-prescribed home protocol costing a fraction of that.

What actually separates providers

After comparing pricing, intake flows and care models across the market, three things separate the best NAD+ programs from the rest:

The real monthly price. Advertised prices are rarely what you pay. Several major providers require a membership on top of the medication - $99/mo at Eden, $74.99/mo at Ivím - which can nearly double the true cost. Our rankings score the all-in number, not the headline.

Physician access. The best programs include the provider consultation, respond in hours rather than days, and let you message a clinician whenever you need a protocol adjustment - without per-visit fees.

Injections, not sprays. NAD+ taken orally is largely destroyed in digestion, and sprays or patches deliver only a fraction of a therapeutic dose with little absorption evidence behind them. Every provider ranked here is scored on its injectable program.

Cold-chain shipping. NAD+ is temperature-sensitive. Providers that ship cold-packed overnight with supplies included remove the most common failure point in home protocols.

What you should expect to pay

Injection programs at reputable providers run from roughly $170 to $325 per month all-in, depending on dose and what’s bundled. First-month promotions are common - RenuviaRX’s $49 first month is the most aggressive we verified - and long-commitment plans (like 12-month terms at Joi + Blokes) can bring injections under $90/mo if you’re certain you’ll stick with the protocol.

Why start now rather than later

NAD+ decline is gradual, which is exactly why most people ignore it until the energy is already gone. The case for starting a supervised protocol earlier is that you establish a baseline with a physician, learn how your body responds while the stakes are low, and adjust from there. The case for waiting: the human evidence base is still maturing. A licensed provider consultation

  • included free with most programs on this page - is the right place to weigh both.
Featured Partner Offer
NAD+ Starting at $49 First Month

Physician-supervised NAD+ injections without a membership fee - see if you qualify in minutes.

Get Started
On RenuviaRX's website

Frequently asked questions

What is NAD+ therapy?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell that plays a central role in energy metabolism and cellular repair. NAD+ levels decline with age, and NAD+ therapy aims to restore them - typically through small subcutaneous injections a few times per week. Telehealth NAD+ programs pair the medication with a licensed provider consultation.

Is NAD+ therapy FDA-approved?

No. NAD+ therapy products sold through telehealth providers are compounded medications prepared by licensed US pharmacies. Compounded medications are not approved or evaluated for safety, effectiveness or quality by the FDA. A licensed provider determines whether a prescription is appropriate for you.

How much does NAD+ therapy cost per month?

Across the injection programs we compared, real all-in pricing runs from about $170 to $325 per month. Watch for membership fees - several providers add $75-$99 per month on top of the advertised medication price. RenuviaRX had the lowest verified entry price at $49 for the first month with no membership fee.

Why injections instead of pills, sprays or patches?

NAD+ is a large, unstable molecule. Taken orally it is largely broken down in digestion, and nasal sprays or skin patches deliver only small amounts with little published absorption evidence. Subcutaneous injection is the one common form that reliably delivers a full, measurable dose - which is why this page ranks injection programs only. Typical protocols are 2-3 small subQ injections per week.

How fast will I feel results?

Providers commonly report that patients notice energy changes within one to two weeks and mental-clarity effects by week three, but individual results vary significantly and robust clinical evidence in humans is still developing. No outcome is guaranteed.

Sources

  1. RenuviaRX - NAD+ Therapy
  2. AgelessRx - NAD+ injections
  3. Eden - NAD+ treatment
  4. Joi + Blokes - NAD+
  5. Ivím Health - NAD+

Providers are scored on pricing transparency, provider access, speed & shipping, and product quality. Pricing verified August 2026. Read our full scoring methodology.